Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682789 | 0.98 | SIRT6 (0.62) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL14471244 | 0.93 | SIRT6 (0.56) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL929209 | 0.87 | KDM4E (0.52) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL12157363 | 0.86 | KDM4E (0.55) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL19860488 | 0.86 | SIRT6 (0.49) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL506609 | 0.85 | SIRT6 (0.67) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL506608 | 0.85 | SIRT6 (0.67) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL930076 | 0.85 | KDM4E (0.53) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL4390415 | 0.84 | SIRT6 (0.48) | SIRT6SIRT1MEN1ALDH1A1HPGD | |
| SCHEMBL4395359 | 0.84 | SIRT6 (0.48) | SIRT6SIRT1MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120407-B1 | Cystine derivatives | AJINOMOTO KK (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-7105570-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-6703031-B1 | OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-6602492-B2 | Cysteine derivatives | AJINOMOTO CO., INC. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1120407-A1 | CYSTEINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |