⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258251 | 1.00 | — | — | |
| SCHEMBL3899168 | 1.00 | — | — | |
| SCHEMBL2808868 | 0.79 | — | — | |
| SCHEMBL2808870 | 0.79 | — | — | |
| SCHEMBL14952925 | 0.76 | PTGS1 (0.39) | — | |
| SCHEMBL14952926 | 0.76 | PTGS1 (0.39) | — | |
| SCHEMBL1396002 | 0.74 | FFAR3 (0.43) | — | |
| SCHEMBL18814 | 0.74 | — | — | |
| SCHEMBL1900173 | 0.74 | PTGS1 (0.55) | — | |
| SCHEMBL3791596 | 0.74 | PTGS1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12623988-B2 | Scaleable preparation of polyketides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-05-12 | — | — | US | disclosed |
| US-20250288549-A1 | SYNTHETIC PROCESS FOR PRODUCTION OF LIPOXIN B4 AND ANALOGUES THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2025-09-18 | — | — | US | disclosed |
| WO-2023205908-A1 | SYNTHETIC PROCESS FOR PRODUCTION OF LIPOXIN B4 AND ANALOGUES THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2023-11-02 | — | — | WO | disclosed |
| US-20230029301-A1 | SCALEABLE PREPARATION OF POLYKETIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-01-26 | — | — | US | disclosed |
| CN-114302721-A | Scalable preparation of polyketones | 加利福尼亚大学董事会 | 2022-04-08 | — | — | CN | disclosed |
| EP-2780336-B1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | PASTEUR INSTITUT (FR) | 2017-07-19 | — | — | EP | disclosed |
| EP-2780336-B1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | PASTEUR INSTITUT (FR) | 2017-07-19 | — | — | EP | disclosed |
| US-9598393-B2 | Structural variants of mycolactones for use in modulating inflammation, immunity and pain | INSTITUT PASTEUR (FR) | 2017-03-21 | — | — | US | disclosed |
| EP-3012257-A1 | Leiodermatolide derivatives and their use | Studiengesellschaft Kohle mbH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-20140329771-A1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | INSTITUT PASTEUR (FR) | 2014-11-06 | — | — | US | disclosed |
| WO-2006017761-A2 | EPOTHILONE ANALOGUES AS THERAPEUTIC AGENTS | EMORY UNIVERSITY (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20040122037-A1 | Isoxazoline derivatives as anti-depressants | JANSSEN-CILAG S.A. (ES) | 2004-06-24 | — | — | US | disclosed |
| CN-1492871-A | Isoxazoline derivatives as anti-depressants | ղɭҩҵ����˾ | 2004-04-28 | — | — | CN | disclosed |
| EP-1368358-A1 | ISOXAZOLINE DERIVATIVES AS ANTI-DEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002066484-A1 | ISOXAZOLINE DERIVATIVES AS ANTI-DEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-29 | — | — | WO | disclosed |
| EP-0642345-B1 | Halichondrins and related compounds | HARVARD COLLEGE (US) | 2000-09-06 | — | — | EP | disclosed |
| US-5436238-A | Halichondrins and related compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0642345-A4 | HALICHONDRINS AND RELATED COMPOUNDS. | HARVARD COLLEGE (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0642345-A1 | HALICHONDRINS AND RELATED COMPOUNDS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993017690-A1 | HALICHONDRINS AND RELATED COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1993-09-16 | — | — | WO | disclosed |