Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR2 | Q8NFJ6 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565026 | 0.90 | PROKR2 (0.50) | PROKR2PKMBCHEMAP3K7TAB1 | |
| SCHEMBL565094 | 0.88 | PROKR2 (0.58) | PROKR2PKMMEN1NPC1RAB9A | |
| SCHEMBL565604 | 0.88 | PROKR2 (0.58) | PROKR2PKMMEN1NPC1RAB9A | |
| SCHEMBL564195 | 0.88 | PROKR2 (0.58) | PROKR2PKMMEN1NPC1RAB9A | |
| SCHEMBL564196 | 0.88 | PROKR2 (0.77) | PROKR2PKMMAP3K7TAB1MEN1 | |
| SCHEMBL565605 | 0.88 | PROKR2 (0.77) | PROKR2PKMMAP3K7TAB1MEN1 | |
| SCHEMBL565095 | 0.88 | PROKR2 (0.77) | PROKR2PKMMAP3K7TAB1MEN1 | |
| SCHEMBL565850 | 0.88 | PROKR2 (0.58) | PROKR2MAP3K7TAB1MAPK8 | |
| SCHEMBL565125 | 0.86 | PROKR2 (0.57) | PROKR2NPC1RAB9AMAPK8 | |
| SCHEMBL565664 | 0.83 | PROKR2 (0.66) | PROKR2PKMMAP3K7TAB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722896-B2 | Prokineticin receptor antagonists and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120035149-A1 | Prokineticin Receptor Antagonists And Uses Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035149-A1 | Prokineticin Receptor Antagonists And Uses Thereof | PROKR2, PROKR1, GIPR | PROKR2 1/4885PKM 722/4885BCHE 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.