SCHEMBL5657014

SCHEMBL5657014

COc1[c]cnc(C)c1O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4481753 0.73
SCHEMBL9656191 0.73
SCHEMBL2263543 0.67 PDE10A (0.40)
SCHEMBL7265294 0.67 KDM4E (0.41)
SCHEMBL312906 0.65 MAOA (0.33)
SCHEMBL3394099 0.64
SCHEMBL28395154 0.62 TP53 (0.33)
SCHEMBL14818692 0.61 PDPK1 (0.38) SMPD3
SCHEMBL9662317 0.61 TP53 (0.41)
SCHEMBL30559672 0.61 PDPK1 (0.38) SMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250389-B1 Antifungal compound and process for producing the same MEIJI SEIKA KAISHA, LTD. (JP) 2007-07-31 US disclosed
EP-1054011-B1 NOVEL ANTIFUNGAL COMPOUNDS AND PROCESS FOR PRODUCING THE SAME MEIJI SEIKA KAISHA (JP) 2006-09-13 EP disclosed
EP-1054011-A1 NOVEL ANTIFUNGAL COMPOUNDS AND PROCESS FOR PRODUCING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 2000-11-22 EP disclosed