Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.43 |
| ▸ | FNTB | P49356 | 6/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13501480 | 0.87 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL1683552 | 0.81 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL13501497 | 0.80 | FNTA (0.45) | FNTAFNTBEPAS1 | |
| SCHEMBL3973432 | 0.79 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL13501499 | 0.79 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL3980315 | 0.78 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7668953 | 0.75 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL11448227 | 0.75 | EPAS1 (0.44) | EPAS1 | |
| SCHEMBL3553870 | 0.74 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL13501477 | 0.74 | FNTA (0.62) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173040-B2 | Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-06 | — | — | US | disclosed |
| US-20040048882-A1 | Farnesyl transferase inhibiting 6-(substituted phenyl) Methy)-quinoline and quinazoline derinazoline derivaties | JANSSEN-CILAG S.A. (FR) | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048882-A1 | Farnesyl transferase inhibiting 6-(substituted phenyl) Methy)-quinoline and quinazoline derinazoline derivaties | FNTB, FNTA, CYP7A1 | FNTA 2/4885FNTB 1/4885EPAS1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.