Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630345 | 0.89 | IDO1 (0.61) | IDO1TDO2 | |
| SCHEMBL4986046 | 0.89 | IDO1 (0.60) | IDO1TDO2 | |
| SCHEMBL5632110 | 0.87 | IDO1 (0.58) | IDO1TDO2 | |
| SCHEMBL5631279 | 0.86 | IDO1 (0.55) | IDO1TDO2 | |
| SCHEMBL5630694 | 0.85 | IDO1 (0.58) | IDO1TDO2 | |
| SCHEMBL15093228 | 0.85 | IDO1 (0.60) | IDO1TDO2 | |
| SCHEMBL5631485 | 0.83 | IDO1 (0.59) | IDO1TDO2 | |
| SCHEMBL5629922 | 0.83 | IDO1 (0.71) | IDO1TDO2 | |
| SCHEMBL5633141 | 0.82 | IDO1 (0.57) | IDO1TDO2 | |
| SCHEMBL5631520 | 0.82 | IDO1 (0.64) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185165-A1 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION | 2007-08-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185165-A1 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, HNMT | IDO1 1/4885TDO2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.