Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 16/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658283 | 0.91 | GRIA2 (0.43) | GRIA2 | |
| SCHEMBL5657223 | 0.87 | GRIA2 (0.57) | GRIA2 | |
| SCHEMBL5351047 | 0.77 | GRIA2 (0.67) | GRIA2 | |
| SCHEMBL5657232 | 0.76 | GRIA2 (0.43) | GRIA2 | |
| SCHEMBL5475951 | 0.74 | GRIA2 (0.68) | GRIA2 | |
| SCHEMBL5183843 | 0.74 | GRIA2 (0.55) | GRIA2 | |
| SCHEMBL5487078 | 0.73 | GRIA2 (0.71) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL5479486 | 0.72 | GRIA2 (0.51) | GRIA2 | |
| SCHEMBL5476903 | 0.72 | GRIA2 (0.51) | GRIA2 | |
| SCHEMBL5359084 | 0.72 | GRIA2 (0.73) | GRIA2GRIA1GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262191-B2 | Benzothiadiazine compounds | LES LABORATORIES SERVIER (FR) | 2007-08-28 | — | — | US | claimed |
| US-20060094713-A1 | New benzothiadiazine compounds | LES LABORATOIRES SERVIER (FR) | 2006-05-04 | — | — | US | claimed |
| US-7262191-B2 | Benzothiadiazine compounds | LES LABORATORIES SERVIER (FR) | 2007-08-28 | — | — | US | disclosed |
| EP-1655299-A1 | Benzothiadiazine derivatives, process of preparation thereof and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-05-10 | — | — | EP | disclosed |
| US-20060094713-A1 | New benzothiadiazine compounds | LES LABORATOIRES SERVIER (FR) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094713-A1 | New benzothiadiazine compounds | SQOR, NDUFS5, GLRX3 | GRIA2 125/4885GRIA1 82/4885GRIA3 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.