Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | PPARA | Q07869 | 17/20 | 0.58 |
| ▸ | PPARD | Q03181 | 4/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658450 | 0.93 | PPARA (0.50) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL14602220 | 0.93 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL14602219 | 0.93 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5657691 | 0.93 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7004233 | 0.92 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7010493 | 0.92 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7009669 | 0.92 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7009193 | 0.92 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7004348 | 0.92 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5660094 | 0.90 | PPARA (0.53) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103215-A1 | New monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR, INC. | 2002-08-01 | — | — | US | claimed |
| US-6369067-B1 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-04-09 | — | — | US | claimed |
| US-7157581-B2 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-02 | — | — | US | disclosed |
| US-7157581-B2 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-02 | — | — | US | disclosed |
| US-7157581-B2 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-02 | — | — | US | disclosed |
| US-7053217-B2 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-05-30 | — | — | US | disclosed |
| US-20060089500-A1 | New monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED | 2006-04-27 | — | — | US | disclosed |
| US-20020103215-A1 | New monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR, INC. | 2002-08-01 | — | — | US | disclosed |
| US-6369067-B1 | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089500-A1 | New monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | CYP11B1, CYP46A1, CYP51A1 | PPARG 141/4885PPARA 187/4885PPARD 154/4885 |
| US-20020103215-A1 | New monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | CYP11B1, CYP46A1, CYP27A1 | PPARG 133/4885PPARA 176/4885PPARD 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.