Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 13/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139286 | 0.82 | HTR6 (0.62) | DRD2KDM4EHSD17B10ALOX15HTR6 | |
| Hydrochloric Acid SCHEMBL27553752 | 0.80 | KDM4E (0.59) | DRD2KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7487134 | 0.74 | KDM4E (0.65) | DRD2KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7482443 | 0.73 | KDM4E (0.50) | DRD2KDM4EALDH1A1MAPTHSD17B10 | |
| Morpholine SCHEMBL27771009 | 0.72 | HTR6 (0.69) | HTR2CHTR6HTR1AHTR7HTR1D | |
| SCHEMBL653742 | 0.72 | KDM4E (1.00) | DRD2KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL29379037 | 0.72 | KDM4E (1.00) | DRD2KDM4EALDH1A1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9960412 | 0.72 | HTR6 (0.54) | DRD2ALDH1A1HTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL3156784 | 0.72 | HTR6 (0.54) | ALDH1A1HTR2CHTR6 | |
| SCHEMBL13333255 | 0.72 | HTR6 (0.76) | HTR2CHTR6HTR1AHTR7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176200-B2 | Derivatives of sulphonamides, their preparation and use as medicaments | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2007-02-13 | — | — | US | claimed |