Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | HRH1 | P35367 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657115 | 0.90 | CCR3 (0.73) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL5658546 | 0.89 | CCR3 (0.68) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL5657759 | 0.87 | HRH3 (0.53) | CCR3HRH3OPRM1OPRD1MEN1 | |
| SCHEMBL6397907 | 0.87 | CCR3 (0.82) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6403935 | 0.87 | CCR3 (0.73) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6397226 | 0.86 | CCR3 (0.72) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6397002 | 0.86 | CCR3 (0.78) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6403438 | 0.85 | CCR3 (0.70) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6398910 | 0.85 | CCR3 (0.70) | CCR3HRH3HRH1KCNH2UTS2R | |
| SCHEMBL6403928 | 0.85 | CCR3 (0.70) | CCR3HRH3HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304077-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2007-12-04 | — | — | US | disclosed |
| US-20040102432-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102432-A1 | Chemical compounds | CCL11, HRH1, HRH4 | CCR3 17/4885HRH3 8/4885HRH1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.