Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133522 | 0.89 | USP2 (0.65) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL4330349 | 0.89 | USP2 (0.65) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL107892 | 0.89 | USP2 (0.65) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| Mannitol SCHEMBL29235000 | 0.76 | LMNA (0.61) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL1086009 | 0.74 | USP2 (0.68) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL8720391 | 0.74 | USP2 (0.68) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL11274631 | 0.74 | — | — | |
| SCHEMBL5658573 | 0.74 | USP2 (0.35) | USP2SLCO1B1 | |
| SCHEMBL149462 | 0.73 | USP2 (0.61) | USP2SLCO1B1LMNAL3MBTL1PDE4A | |
| SCHEMBL21057 | 0.73 | USP2 (0.61) | USP2SLCO1B1LMNAL3MBTL1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3525886-A1 | COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts (DE) | 2019-08-21 | — | — | EP | claimed |
| WO-2018069525-A1 | COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2018-04-19 | — | — | WO | claimed |
| EP-3921647-A1 | IMPROVED DITHIOCARMABATE BASED COMPOUNDS, THERAPIES AND DIAGNOSTICS | Deutsches Krebsforschungszentrum - Stiftung des öffentlichen Rechts / Universität Heidelberg (DE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020161337-A1 | IMPROVED DITHIOCARMABATE BASED COMPOUNDS, THERAPIES AND DIAGNOSTICS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2020-08-13 | — | — | WO | disclosed |
| EP-3525886-A1 | COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts (DE) | 2019-08-21 | — | — | EP | disclosed |
| WO-2018069525-A1 | COMPOSITIONS COMPRISING A METAL SOURCE, DITHIOCARBAMATE AND CYCLODEXTRIN | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2018-04-19 | — | — | WO | disclosed |
| EP-1328267-A4 | METHOD OF TREATING CANCER USING DITHIOCARBAMATE DERIVATIVES | CHARLOTTE MECKLENBURG HOSPITAL (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1328267-A2 | METHOD OF TREATING CANCER USING DITHIOCARBAMATE DERIVATIVES | Charlotte-Mecklenburg Hospital Authority doing business as Carolinas Medical Center (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002028349-A2 | METHOD OF TREATING CANCER USING DITHIOCARBAMATE DERIVATIVES | CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY, DOING BUSINESS AS CAROLINAS MEDICAL CENTER (US) | 2002-04-11 | — | — | WO | disclosed |