Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.71 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659711 | 0.99 | DRD2 (0.72) | DRD2MCHR1ADRA1A | |
| SCHEMBL5660504 | 0.92 | DRD2 (0.77) | DRD2MCHR1 | |
| SCHEMBL5661618 | 0.92 | DRD2 (0.77) | DRD2MCHR1 | |
| SCHEMBL5661038 | 0.91 | DRD2 (0.79) | DRD2MCHR1ADRA1A | |
| SCHEMBL5659940 | 0.91 | DRD2 (0.78) | DRD2 | |
| SCHEMBL5658991 | 0.91 | DRD2 (0.78) | DRD2 | |
| SCHEMBL5660921 | 0.90 | DRD2 (0.80) | DRD2 | |
| SCHEMBL5660025 | 0.89 | DRD2 (0.73) | DRD2 | |
| SCHEMBL14619720 | 0.89 | DRD2 (0.73) | DRD2MCHR1 | |
| SCHEMBL5660239 | 0.89 | DRD2 (0.80) | DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
| US-7067534-B1 | Substituted anilinic piperidines as MCH selective antagonists | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-6727264-B1 | MELANIN CONCENTRATING HORMONE-1 RECEPTOR ANTAGONISTS; SLEEP, EATING, SEXUAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | DRD2 119/4885MCHR1 1/4885ADRA1A 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.