SCHEMBL5659319

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9118735	0.90	CYP3A4 (0.53)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL9119911	0.88	CYP3A4 (0.59)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL15428220	0.79	CYP3A4 (0.53)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL8698375	0.79	CA1 (0.47)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL9428752	0.78	CYP3A4 (0.43)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL9700196	0.78	CYP3A4 (0.59)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL10585725	0.78	CYP2C19 (0.45)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL6103008	0.78	LMNA (0.44)	CYP3A4ALDH1A1KDM4EMAPTTDP1
	SCHEMBL8846326	0.77	CYP3A4 (0.61)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2
	SCHEMBL9559982	0.77	CYP3A4 (0.61)	CYP3A4ALDH1A1KDM4EMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.