Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11596441 | 0.98 | GAA (0.56) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL2748971 | 0.90 | KDM4E (0.60) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL2062891 | 0.90 | SMPD1 (0.56) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL21295357 | 0.88 | MAOB (0.58) | MAOBGAAMAPTL3MBTL1MAOA | |
| Hydrochloric Acid SCHEMBL15487723 | 0.88 | KDM4E (0.63) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30744016 | 0.88 | MAOB (0.58) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL15814937 | 0.87 | CYP19A1 (0.50) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL11372714 | 0.87 | MAPT (0.56) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL8298067 | 0.87 | MAOB (0.56) | MAOBGAAMAPTL3MBTL1MAOA | |
| SCHEMBL11857933 | 0.85 | CYP19A1 (0.57) | MAOBGAAMAPTL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055355-A | Compounds for the treatment of diabetes and related disorders | 奥克兰联合服务有限公司 | 2026-05-15 | — | — | CN | disclosed |
| WO-2025042293-A1 | COMPOUNDS FOR TREATING DIABETES AND RELATED CONDITIONS | AUCKLAND UNISERVICES LIMITED (NZ) | 2025-02-27 | — | — | WO | disclosed |
| US-20240199561-A1 | INHIBITORS OF DYRK AND PIM | COLD SPRING HARBOR LABORATORY (US) | 2024-06-20 | — | — | US | disclosed |
| EP-4281442-A1 | INHIBITORS OF DYRK AND PIM | COLD SPRING HARBOR LABORATORY (US) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023171231-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | キヤノン株式会社 | 2023-09-14 | — | — | WO | disclosed |
| WO-2022159436-A1 | INHIBITORS OF DYRK AND PIM | COLD SPRING HARBOR LABORATORY (US) | 2022-07-28 | — | — | WO | disclosed |
| US-7745490-B2 | Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies | PROTEOTECH, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745490-B2 | Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies | PROTEOTECH, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20090060838-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH INC. | 2009-03-05 | — | — | US | disclosed |
| US-20090060838-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | PROTEOTECH INC. | 2009-03-05 | — | — | US | disclosed |
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4326075-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4203920-A | ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4163015-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4138405-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4115564-A | Treatment of diarrhea with amidinoureas | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4060635-A | Amidinoureas for treating diarrhea | WILLIAM H. RORER, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4025652-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1977-05-24 | — | — | US | disclosed |
| US-3995041-A | CORONARY VASODILATORS | MILES LABORATORIES, INC. (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090060838-A1 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES | IAPP, SNCA, BACE2 | MAOB 197/4885GAA 53/4885MAPT 40/4885 |
| US-20240199561-A1 | INHIBITORS OF DYRK AND PIM | PIM3, PIM2, PIM1 | MAOB 803/4885GAA 2261/4885MAPT 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.