Sugi Predict

Sugi Predict / Compounds / SCHEMBL2748971

SCHEMBL2748971

SCHEMBL2748971

COc1cc(N)ccc1OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.60
▸ GAA P10253 2/20 0.60
▸ MAPT P10636 2/20 0.60
▸ RAB9A P51151 4/20 0.57
▸ NPC1 O15118 3/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ HPGD P15428 1/20 0.57
▸ CYP19A1 P11511 2/20 0.55
▸ MEN1 O00255 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ CYP1A2 P05177 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ BLM P54132 1/20 0.53
▸ CSF1R P07333 1/20 0.53
▸ HTR1A P08908 1/20 0.53
▸ ADRA1D P25100 1/20 0.53
▸ ADRA1A P35348 1/20 0.53
▸ ADRA1B P35368 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15487723 0.98 KDM4E (0.63) KDM4EGAAMAPTRAB9ANPC1
SCHEMBL2062891 0.93 SMPD1 (0.56) KDM4EGAAMAPTRAB9ASMN1; SMN2
SCHEMBL5659691 0.90 MAOB (0.58) GAAMAPTRAB9ASMN1; SMN2CYP19A1
Hydrochloric Acid SCHEMBL11596441 0.88 GAA (0.56) KDM4EGAAMAPTRAB9ASMN1; SMN2
SCHEMBL11089861 0.85 GAA (0.58) KDM4EGAAMAPTRAB9ANPC1
SCHEMBL15814937 0.84 CYP19A1 (0.50) GAAMAPTRAB9ASMN1; SMN2CYP19A1
SCHEMBL1578459 0.84 KDM4E (0.57) KDM4EGAAMAPTSMN1; SMN2HPGD
SCHEMBL1406548 0.83 MAOB (0.60) KDM4EGAAMAPTSMN1; SMN2MEN1
SCHEMBL5503430 0.83 SMPD1 (0.50) KDM4ERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL67744 0.83 KDM4E (0.68) KDM4EMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106745722-A A kind of mobile tunnel type anaerobic pond support meanss and its method of work 徐州工程学院 2017-05-31 — — CN claimed
EP-0113432-A1 Chloromethyl quinoline derivatives, process for their preparation and their use ALKALOIDA VEGYéSZETI GYáR (HU) 1984-07-18 — — EP claimed
US-12595245-B2 Inhibitors of MET kinase CELYN THERAPEUTICS, INC. (US) 2026-04-07 — — US disclosed
EP-4448510-A1 INHIBITORS OF MET KINASE Kinnate Biopharma Inc. (US) 2024-10-23 — — EP disclosed
CN-118742542-A Inhibitors of MET kinase 金耐特生物制药公司 2024-10-01 — — CN disclosed
US-20240067626-A1 INHIBITORS OF MET KINASE CELYN THERAPEUTICS, INC. 2024-02-29 — — US disclosed
CN-117466897-A Highly selective FGFR2 inhibitors 深圳福沃药业有限公司 2024-01-30 — — CN disclosed
US-11753395-B2 Inhibitors of MET kinase KINNATE BIOPHARMA INC. (US) 2023-09-12 — — US disclosed
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-09-07 — — US disclosed
US-20230219929-A1 INHIBITORS OF MET KINASE CELYN THERAPEUTICS, INC. 2023-07-13 — — US disclosed
WO-2023114809-A1 INHIBITORS OF MET KINASE KINNATE BIOPHARMA INC. (US) 2023-06-22 — — WO disclosed
EP-0782570-A1 SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE THE WELLCOME FOUNDATION LIMITED (GB) 1997-07-09 — — EP disclosed
WO-1996009294-A1 SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE THE WELLCOME FOUNDATION LIMITED (GB) 1996-03-28 — — WO disclosed
EP-0639973-A1 DIAMINES IN THE TREATMENT OF ARRHYTHMIA SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) 1995-03-01 — — EP disclosed
WO-1993023024-A1 DIAMINES IN THE TREATMENT OF ARRHYTHMIA SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) 1993-11-25 — — WO disclosed
EP-0113922-A2 Process for the manufacture of cationic methine dyes BAYER AG (DE) 1984-07-25 — — EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 — — EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 — — EP disclosed
EP-0113432-A1 Chloromethyl quinoline derivatives, process for their preparation and their use ALKALOIDA VEGYéSZETI GYáR (HU) 1984-07-18 — — EP disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595245-B2 Inhibitors of MET kinase MET, ABL1, ERBB2 KDM4E 393/4885GAA 1837/4885MAPT 2891/4885
US-20230219929-A1 INHIBITORS OF MET KINASE MET, RET, MERTK KDM4E 824/4885GAA 2317/4885MAPT 2041/4885
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF AADAC, CBR3, MTCL3 KDM4E 2383/4885GAA 3465/4885MAPT 2830/4885
US-11753395-B2 Inhibitors of MET kinase MET, RET, MERTK KDM4E 824/4885GAA 2317/4885MAPT 2041/4885
US-20240067626-A1 INHIBITORS OF MET KINASE MET, RET, MERTK KDM4E 824/4885GAA 2317/4885MAPT 2041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.