Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023526 | 0.87 | CNR1 (0.59) | TRPV1 | |
| SCHEMBL4023576 | 0.80 | ALDH1A1 (0.69) | TRPV1 | |
| SCHEMBL4024825 | 0.79 | ALDH1A1 (0.67) | TRPV1 | |
| SCHEMBL4026832 | 0.79 | ALDH1A1 (0.67) | TRPV1 | |
| SCHEMBL13595613 | 0.78 | EPHX1 (0.72) | TRPV1 | |
| SCHEMBL14589060 | 0.78 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4026884 | 0.78 | TRPV1 (0.87) | TRPV1 | |
| SCHEMBL14860966 | 0.77 | EPHX1 (0.70) | TRPV1 | |
| SCHEMBL5660097 | 0.76 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL4020202 | 0.76 | TRPV1 (0.58) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285563-B2 | Heteroaromatic urea derivatives as VR-1 receptor modulators for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2007-10-23 | — | — | US | disclosed |
| US-20050107388-A1 | Heteroaromatic urea derivatives as vr-1receptor modulators for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107388-A1 | Heteroaromatic urea derivatives as vr-1receptor modulators for treating pain | ARRB1, OPRL1, CNR1 | TRPV1 37/4885PRMT3 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.