Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.59 |
| ▸ | PPARA | Q07869 | 10/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659640 | 0.91 | PPARD (0.49) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL5661290 | 0.89 | PPARD (0.55) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5660103 | 0.89 | PPARD (0.54) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL5657706 | 0.87 | PPARD (0.55) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL5015494 | 0.78 | PPARD (0.60) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5015502 | 0.78 | PPARD (0.62) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6489153 | 0.78 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6487449 | 0.76 | PPARD (0.62) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5015393 | 0.75 | PPARD (0.58) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5015410 | 0.74 | PPARD (0.65) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072904-A1 | 1-arylsulfone-substituted indole carboxylic acids or amides; peroxisome proliferator-activated receptor PPAR modulators; obesity, diabetes, cardiovascular disorders | PLEXXIKON INC | 2007-03-29 | — | — | US | disclosed |
| US-20070072904-A1 | 1-arylsulfone-substituted indole carboxylic acids or amides; peroxisome proliferator-activated receptor PPAR modulators; obesity, diabetes, cardiovascular disorders | PLEXXIKON INC | 2007-03-29 | — | — | US | disclosed |
| US-20070072904-A1 | 1-arylsulfone-substituted indole carboxylic acids or amides; peroxisome proliferator-activated receptor PPAR modulators; obesity, diabetes, cardiovascular disorders | PLEXXIKON INC | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072904-A1 | 1-arylsulfone-substituted indole carboxylic acids or amides; peroxisome proliferator-activated receptor PPAR modulators; obesity, diabetes, cardiovascular disorders | PPARG, PPARA, PPARD | PPARD 3/4885PPARA 2/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.