SCHEMBL566019

SCHEMBL566019

C1=CCC([Zr]C2c3ccccc3-c3ccccc32)=C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.34
HTR2A P28223 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4639609 0.98 GPR3 (0.33) GPR3
Cyclopentane SCHEMBL8998587 0.97 BCHE (0.34) GPR3
Hydrochloric Acid SCHEMBL8034004 0.94 GPR3 (0.31) GPR3
SCHEMBL9562057 0.92 GPR3 (0.30) GPR3
SCHEMBL9403907 0.92 GPR3 (0.30) GPR3
SCHEMBL5389793 0.78
SCHEMBL6910610 0.77 GPR3 (0.31) GPR3
Hydrochloric Acid SCHEMBL8632927 0.77 ESR1 (0.31)
SCHEMBL7540289 0.76
SCHEMBL7026937 0.73 CYP19A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659773-B1 Production of polyolefins containing long chain branches by a gas phase process UNION CARBIDE CHEM PLASTIC (US) 1998-08-19 EP claimed
EP-0516019-B1 Process for preparing syndiotactic polyolefins with large molecular weight distribution HOECHST AG (DE) 1995-12-27 EP claimed
EP-2663400-A1 PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF W. R. Grace & Co.-Conn (US) 2013-11-20 EP disclosed
US-8507608-B2 Propylene polymer resin composition TOSOH CORPORATION (JP) 2013-08-13 US disclosed
EP-2623560-A1 RESIN COMPOSITION FOR INJECTION MOLDING, INJECTION MOLDED FOAM ARTICLE, AND METHOD FOR PRODUCING INJECTION MOLDED FOAM ARTICLE Tosoh Corporation (JP) 2013-08-07 EP disclosed
EP-2420537-B1 PROPYLENE POLYMER RESIN COMPOSITION TOSOH CORP (JP) 2013-06-05 EP disclosed
CN-102791750-A Ethylene-alpha-olefin copolymer and molded article SUMITOMO CHEMICAL CO 2012-11-21 CN disclosed
WO-2012097146-A1 PROCESS OF MAKING MODIFIED METALLOCENE CATALYST, CATALYST PRODUCED AND USE THEREOF W. R. GRACE & CO.-CONN. (US) 2012-07-19 WO disclosed
EP-2420537-A1 PROPYLENE POLYMER RESIN COMPOSITION Tosoh Corporation (JP) 2012-02-22 EP disclosed
US-20120035290-A1 PROPYLENE POLYMER RESIN COMPOSITION TOSOH CORPORATION (JP) 2012-02-09 US disclosed
CN-1271099-C Process for the oligomerization of alpha olefins having low unsaturation, the resulting polymers, and lubricants containing same UNIROYAL CHEM CO INC (US) 2006-08-23 CN disclosed
CN-1263113-A Stable metallocene polyolefine CIBA SPECIALS HOLDING INC (CH) 2000-08-16 CN disclosed
US-6048817-A Polymerization of olefins MITSUBISHI CHEMICAL CORPORATION (JP) 2000-04-11 US disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
EP-0530908-B1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1999-04-21 EP disclosed
US-5874512-A HYDROCARBON TACKIFIER RESIN WHICH IS THE POLYMERIZATION REACTION PRODUCT OF AT LEAST ONE ALPHA-OLEFIN, AT LEAST ONE CYCLIC OLEFIN, AND AT LEAST ONE AROMATIC-GROUP-CONTAINING MONOMER FARLEY JAMES MCCLEOD (US) 1999-02-23 US disclosed
EP-0874006-A1 Polymerisation of olefins MITSUBISHI CHEMICAL CORPORATION (JP) 1998-10-28 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed
EP-0530908-A1 Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1993-03-10 EP disclosed