SCHEMBL566028

SCHEMBL566028

C1=CC([Zr]C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.33
HTR6 P50406 1/20 0.33
CYP2D6 P10635 2/20 0.33
GPR3 P46089 1/20 0.31
KDM4E B2RXH2 3/20 0.31
LMNA P02545 2/20 0.31
HSD17B10 Q99714 2/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474414 0.84 HTR2A (0.40) HTR2AHTR6CYP2D6KDM4ELMNA
SCHEMBL60674 0.84 HTR2A (0.40) HTR2AHTR6CYP2D6KDM4ELMNA
Methane SCHEMBL5838564 0.82 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ELMNA
SCHEMBL28278996 0.82 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ELMNA
Hydrochloric Acid SCHEMBL5838117 0.82 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ELMNA
SCHEMBL27597712 0.82 HTR2A (0.39) HTR2AHTR6CYP2D6KDM4ELMNA
Hydrochloric Acid SCHEMBL820050 0.80 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4ELMNA
Ethylene SCHEMBL782495 0.80 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4ELMNA
Hydrochloric Acid SCHEMBL7941881 0.80 HTR2A (0.38) HTR2AHTR6CYP2D6KDM4ELMNA
Fluoromethane SCHEMBL8734234 0.79 HTR2A (0.36) HTR2AHTR6CYP2D6KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112239474-A Silicon-based bridged polysubstituted indene-fluorene zirconium and hafnium complex and application thereof in high-temperature polymerization of olefin 惠生(泰州)新材料科技有限公司 2021-01-19 CN disclosed
US-8507608-B2 Propylene polymer resin composition TOSOH CORPORATION (JP) 2013-08-13 US disclosed
EP-2623560-A1 RESIN COMPOSITION FOR INJECTION MOLDING, INJECTION MOLDED FOAM ARTICLE, AND METHOD FOR PRODUCING INJECTION MOLDED FOAM ARTICLE Tosoh Corporation (JP) 2013-08-07 EP disclosed
EP-2420537-B1 PROPYLENE POLYMER RESIN COMPOSITION TOSOH CORP (JP) 2013-06-05 EP disclosed
EP-2420537-A1 PROPYLENE POLYMER RESIN COMPOSITION Tosoh Corporation (JP) 2012-02-22 EP disclosed
US-20120035290-A1 PROPYLENE POLYMER RESIN COMPOSITION TOSOH CORPORATION (JP) 2012-02-09 US disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed