SCHEMBL60674

SCHEMBL60674

C1=CC([Zr]C2C=Cc3ccccc32)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.40
HTR6 P50406 1/20 0.39
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP2D6 P10635 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474414 1.00 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL28278996 0.98 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Methane SCHEMBL5838564 0.98 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL5838117 0.98 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ECYP2D6
SCHEMBL27597712 0.98 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL7941881 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Ethylene SCHEMBL782495 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Hydrochloric Acid SCHEMBL820050 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Chloromethane SCHEMBL3681238 0.94 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6
Fluoromethane SCHEMBL8734234 0.94 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-20 US claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US claimed
EP-3697822-B1 MIXED CATALYSTS WITH UNBRIDGED HAFNOCENES WITH -CH2-SIME3 MOIETIES EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-07-30 EP claimed
CN-120202228-A Method for preparing polyolefin by cascade polymerization 浙江大学衢州研究院 2025-06-24 CN claimed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US claimed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP claimed
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US claimed
EP-3583140-B1 SUPPORTED CATALYST SYSTEMS AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-03-08 EP claimed
US-20220289879-A1 Polymers of 4-Substituted Hexadiene and Processes for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-09-15 US claimed
EP-3568420-B1 HIGH PURITY POLYPROPYLENES AND POLYPROPYLENE COMPOSITIONS FOR MOLDING TOTAL RES & TECHNOLOGY FELUY (BE) 2020-11-18 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
EP-0720989-A1 Continuous process for the (co)polymerization of ethylene ENICHEM S.p.A. (IT) 1996-07-10 EP claimed
EP-0717660-A1 CATALYST PRECURSOR COMPOSITION, AND METHOD OF MAKING THE SAME MOBIL OIL CORPORATION (US) 1996-06-26 EP claimed
EP-0484405-B1 SUPPORTED CATALYST FOR 1-OLEFIN AND 1,4-DIOLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC (US) 1996-05-29 EP claimed
US-5491207-A COORDINATION CATALYST WITH ORGANOALUMINUM COMPOUND EXXON CHEMICAL PATENTS INC. (US) 1996-02-13 US claimed
US-5455214-A Metallocenes supported on ion exchange resins MOBIL OIL CORPORATION (US) 1995-10-03 US claimed
WO-1995007140-A1 CATALYST PRECURSOR COMPOSITION, AND METHOD OF MAKING THE SAME MOBIL OIL CORPORATION (US) 1995-03-16 WO claimed
EP-0389981-B1 Process for producing styrene-based polymer IDEMITSU KOSAN CO (JP) 1994-09-07 EP claimed
EP-0303519-B1 POLYMERIZATION OF ETHYLENE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-03-31 EP claimed
EP-0272584-B1 PROCESS FOR PRODUCING CRYSTALLINE VINYL AROMATIC POLYMERS HAVING A PREDOMINANTLY SYNDIOTACTIC STRUCTURE Montedison S.p.A. (IT) 1992-11-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528892-B2 Alkylation of transition metal coordination catalyst complexes LEF1, TAF1, FLI1 HTR2A 3365/4885HTR6 4173/4885SIGMAR1 880/4885
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes AS3MT, AP1M1, AP3M1 HTR2A 4311/4885HTR6 4581/4885SIGMAR1 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.