Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.63 |
| ▸ | PDE4A | P27815 | 13/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565667 | 0.88 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15661340 | 0.84 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15662761 | 0.78 | PDE4B (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL565769 | 0.77 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15662692 | 0.77 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15662756 | 0.76 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL12431105 | 0.75 | PDE4B (0.88) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL564733 | 0.75 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL564691 | 0.73 | PDE4B (0.84) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL566081 | 0.73 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145429-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20140200198-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-07-17 | — | — | US | disclosed |
| US-8716478-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20120035132-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200198-A1 | BORON-CONTAINING SMALL MOLECULES | BTD, BCL6B, BBOX1 | PDE4B 936/4885PDE4A 1744/4885PDE4C 2197/4885 |
| US-20120035132-A1 | BORON-CONTAINING SMALL MOLECULES | BTD, BCL6B, BBOX1 | PDE4B 936/4885PDE4A 1744/4885PDE4C 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.