Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565403 | 0.90 | KDM4E (0.40) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL566311 | 0.84 | CNR1 (0.42) | MAPK1LMNACSNK2A1MEN1KMT2A | |
| SCHEMBL566214 | 0.75 | POLB (0.43) | KDM4EATMTSHRMAPK1LMNA | |
| SCHEMBL566216 | 0.74 | HDAC11 (0.38) | TAAR1CSNK2A1HDAC11 | |
| SCHEMBL7310155 | 0.74 | KDM4E (0.59) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL565245 | 0.74 | HDAC11 (0.43) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10139272 | 0.73 | S1PR1 (0.39) | LMNAKCNH2TMEM97SIGMAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL566087 | 0.72 | S1PR1 (0.39) | LMNAKCNH2TMEM97SIGMAR1CYP3A4 | |
| SCHEMBL566215 | 0.72 | HDAC11 (0.38) | TAAR1LMNACSNK2A1MEN1KMT2A | |
| SCHEMBL7691709 | 0.72 | HDAC11 (0.42) | LMNACSNK2A1MEN1KMT2AHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | KDM4E 1701/4885ATM 3271/4885TAAR1 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.