Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592835 | 0.84 | RAB9A (0.61) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5593306 | 0.82 | MEN1 (0.65) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5593021 | 0.82 | MAPT (0.64) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5593104 | 0.82 | RAB9A (0.61) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5592819 | 0.77 | MEN1 (0.67) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5593073 | 0.75 | RAB9A (0.65) | MAPTKDM4ELMNANPSR1HTT | |
| SCHEMBL5616533 | 0.75 | MAPT (0.57) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL29839421 | 0.73 | KMT2A (0.53) | MAPTKDM4EPOLBLMNANPSR1 | |
| SCHEMBL5611752 | 0.73 | MAPT (0.57) | MAPTKDM4ELMNANPSR1HTT | |
| SCHEMBL5592813 | 0.73 | RAB9A (0.58) | MAPTKDM4EPOLBLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |