Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 18/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663596 | 1.00 | MTTP (0.43) | MTTPDRD1DRD4DRD5HTR2C | |
| SCHEMBL5665959 | 0.94 | MTTP (0.48) | MTTP | |
| SCHEMBL5665964 | 0.94 | MTTP (0.48) | MTTP | |
| SCHEMBL5664213 | 0.90 | MTTP (0.47) | MTTP | |
| SCHEMBL5664217 | 0.90 | MTTP (0.47) | MTTP | |
| SCHEMBL5664786 | 0.87 | MTTP (0.43) | MTTP | |
| SCHEMBL5664782 | 0.87 | MTTP (0.43) | MTTP | |
| SCHEMBL5664446 | 0.84 | MTTP (0.52) | MTTP | |
| SCHEMBL5664451 | 0.84 | MTTP (0.52) | MTTP | |
| SCHEMBL5665922 | 0.83 | MTTP (0.52) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716137-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080373-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |