SCHEMBL5665959

SCHEMBL5665959

CCCCCNC(=O)[C@H](c1ccccc1)N(C)Cc1ccc2nc(NC(=O)c3cccnc3-c3ccc(C(F)(F)F)cc3)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MTTP P55157 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5665964 1.00 MTTP (0.48) MTTP
SCHEMBL5663591 0.94 MTTP (0.43) MTTP
SCHEMBL5663596 0.94 MTTP (0.43) MTTP
SCHEMBL5664446 0.90 MTTP (0.52) MTTP
SCHEMBL5664451 0.90 MTTP (0.52) MTTP
SCHEMBL5665928 0.88 MTTP (0.52) MTTP
SCHEMBL5665922 0.88 MTTP (0.52) MTTP
SCHEMBL5666615 0.87 MTTP (0.49) MTTP
SCHEMBL5666609 0.87 MTTP (0.49) MTTP
SCHEMBL5664213 0.84 MTTP (0.47) MTTP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1716137-A1 SUBSTITUTED QUINOLINE COMPOUNDS Pfizer Products Incorporated (US) 2006-11-02 — — EP disclosed
WO-2005080373-A1 SUBSTITUTED QUINOLINE COMPOUNDS PFIZER PRODUCTS INC. (US) 2005-09-01 — — WO disclosed
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