Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 17/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665941 | 0.93 | PTAFR (0.42) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5664536 | 0.90 | OPRK1 (0.45) | PTAFROPRK1PDE4D | |
| SCHEMBL5663627 | 0.90 | OPRK1 (0.48) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5664049 | 0.89 | PTAFR (0.43) | PTAFROPRK1PDE4D | |
| SCHEMBL5664178 | 0.89 | PTAFR (0.48) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5666605 | 0.88 | PTAFR (0.46) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5664204 | 0.87 | PTAFR (0.45) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5663624 | 0.87 | PTAFR (0.45) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5663663 | 0.87 | PTAFR (0.42) | PTAFROPRK1PDE4DTBXAS1 | |
| SCHEMBL5664102 | 0.87 | OPRK1 (0.42) | PTAFROPRK1PDE4DTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015213-B1 | Use of diazepines for preparing medicines for treating pathological conditions or diseases involving one of the growth hormone release inhibiting factor receptors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-03-21 | — | — | US | claimed |
| US-7015213-B1 | Use of diazepines for preparing medicines for treating pathological conditions or diseases involving one of the growth hormone release inhibiting factor receptors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-03-21 | — | — | US | disclosed |