Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.51 |
| ▸ | MTTP | P55157 | 3/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666303 | 0.90 | MTTP (0.56) | TRPV1MTTP | |
| SCHEMBL2842480 | 0.85 | MTTP (0.61) | MTTP | |
| SCHEMBL5665507 | 0.85 | MTTP (0.49) | TRPV1MTTPSORT1 | |
| SCHEMBL4993382 | 0.84 | MTTP (0.59) | MTTP | |
| SCHEMBL4986283 | 0.84 | MTTP (0.59) | MTTP | |
| SCHEMBL27673052 | 0.83 | MTTP (0.53) | MTTP | |
| SCHEMBL27673054 | 0.83 | MTTP (0.53) | MTTP | |
| SCHEMBL4986532 | 0.82 | MTTP (0.49) | MTTPSORT1 | |
| SCHEMBL6765865 | 0.82 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL5664685 | 0.81 | MTTP (0.51) | TRPV1MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914195-A | Substituted quinoline compounds | PFIZER PROD INC (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-1716137-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080373-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |