Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915789 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6915887 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6915788 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6916678 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6909969 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6913595 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6916682 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6916880 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6918684 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6909967 | 0.98 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630552-B2 | Inhibitors of KRAS G12C | BEONE MEDICINES I GMBH (CH) | 2026-05-19 | — | — | US | disclosed |
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | BEONE MEDICINES I GMBH (CH) | 2022-12-08 | — | — | US | disclosed |
| CN-114929706-A | Inhibitors of KRAS G12C | 百济神州有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2022067462-A1 | PROCESS FOR PREPARING INHIBITORS OF KRAS G12C | BEIGENE (BEIJING) CO., LTD. (CN) | 2022-04-07 | — | — | WO | disclosed |
| WO-2021058018-A1 | INHIBITORS OF KRAS G12C | BEIGENE, LTD. (KY) | 2021-04-01 | — | — | WO | disclosed |
| EP-2465841-A1 | Preparation of esters of mono- or dicarboxylic non-aromatic and aromatic acids | Lonza Ltd. (CH) | 2012-06-20 | — | — | EP | disclosed |
| US-20060128823-A1 | Radiation curable inkjet recording ink, and method of producing planographic printing plate using same, and ink composition, inkjet recording method, printed material, method of producing a planographic printing plate, and planographic printing plate | FUJI PHOTO FILM CO., LTD. | 2006-06-15 | — | — | US | disclosed |
| EP-1657286-A2 | Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye | FUJI PHOTO FILM CO., LTD. (JP) | 2006-05-17 | — | — | EP | disclosed |
| US-4224225-A | PHOTOPOLYMERIZATION INITIATOR | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389021-A1 | INHIBITORS OF KRAS G12C | KRAS, NRAS, HRAS | ALDH1A1 3777/4885MEN1 895/4885KMT2A 2234/4885 |
| US-12630552-B2 | Inhibitors of KRAS G12C | KRAS, NRAS, HRAS | ALDH1A1 1940/4885MEN1 1397/4885KMT2A 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.