Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134655 | 0.84 | TLR7 (0.38) | TLR7NUDT1ALDH1A1POLBNCF1 | |
| SCHEMBL28872949 | 0.78 | SCN9A (0.52) | NUDT1ALDH1A1TSHRSCN9ALMNA | |
| SCHEMBL3023761 | 0.76 | TLR7 (0.50) | TLR7NUDT1NCF1TSHRMPO | |
| Hydrochloric Acid SCHEMBL3231113 | 0.75 | TLR7 (0.49) | TLR7NUDT1NCF1TSHRMPO | |
| SCHEMBL28484277 | 0.73 | TSHR (0.43) | TLR7NUDT1ALDH1A1POLBNCF1 | |
| SCHEMBL5665202 | 0.72 | KDR (0.42) | KDM1A | |
| SCHEMBL27945207 | 0.72 | TSHR (0.55) | ALDH1A1POLBNCF1TSHRL3MBTL1 | |
| SCHEMBL6380647 | 0.72 | TLR7 (0.45) | TLR7NUDT1NCF1TSHRMPO | |
| SCHEMBL8682782 | 0.71 | TSHR (0.46) | TLR7NUDT1ALDH1A1POLBNCF1 | |
| SCHEMBL5664809 | 0.69 | LDHA (0.40) | TSHRL3MBTL1MPOADORA2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | TLR7 1532/4885NUDT1 1602/4885ALDH1A1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.