Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073321 | 0.84 | ATM (1.00) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2457624 | 0.83 | ALDH1A1 (0.74) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28881222 | 0.83 | HDAC8 (0.77) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5419548 | 0.80 | ATM (0.58) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4258833 | 0.79 | HDAC8 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19881938 | 0.77 | ATM (0.55) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5398361 | 0.77 | HDAC8 (0.60) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1149847 | 0.76 | CYP2C9 (0.60) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4848806 | 0.75 | ATM (0.57) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20458727 | 0.72 | ATM (0.54) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161643-A1 | Pyridin-2-one compounds useful as inhibitors of thrombin | ASTRAZENECA AB (SE) | 2007-07-12 | — | — | US | disclosed |
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161643-A1 | Pyridin-2-one compounds useful as inhibitors of thrombin | PLG, F2, PLAT | ATM 2177/4885HDAC3 1473/4885HDAC4 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.