Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.80 |
| ▸ | GSR | P00390 | 2/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL5664976 | 1.00 | PTGS1 (0.80) | PTGS1SLC7A11GSRCPB2ENPEP | |
| Cysteine SCHEMBL6014745 | 0.95 | PTGS1 (0.73) | PTGS1SLC7A11GSRCPB2ENPEP | |
| Cysteine SCHEMBL6014744 | 0.95 | PTGS1 (0.73) | PTGS1SLC7A11GSRCPB2ENPEP | |
| Cysteine SCHEMBL15418989 | 0.92 | PTGS1 (0.84) | PTGS1SLC7A11GSRCPB2ENPEP | |
| Cysteine SCHEMBL15417993 | 0.92 | PTGS1 (0.84) | PTGS1SLC7A11GSRCPB2ENPEP | |
| Cysteine SCHEMBL5705430 | 0.89 | PTGS1 (1.00) | PTGS1SLC7A11GSRENPEPGRIK1 | |
| Cysteine SCHEMBL95110 | 0.89 | — | — | |
| Cysteine SCHEMBL21110883 | 0.89 | PTGS1 (1.00) | PTGS1SLC7A11GSRENPEPGRIK1 | |
| Cysteine SCHEMBL1868335 | 0.89 | PTGS1 (1.00) | PTGS1SLC7A11GSRENPEPGRIK1 | |
| Cysteine SCHEMBL7898895 | 0.89 | PTGS1 (1.00) | PTGS1SLC7A11GSRENPEPGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919178-B2 | Extended tethering approach for rapid identification of ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2005-07-19 | — | — | US | claimed |
| EP-0547102-A4 | — | — | 1994-04-27 | — | — | EP | claimed |
| EP-0547102-A1 | SOLUBILIZATION OF PROTEINS IN ACTIVE FORMS | SOUTHERN CROSS BIOTECH PTY.LTD. (AU) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004382-A1 | SOLUBILIZATION OF PROTEINS IN ACTIVE FORMS | BUNGE (AUSTRALIA) PTY. LTD. (AU) | 1992-03-19 | — | — | WO | claimed |
| EP-1513866-A4 | ASSAY CONJUGATE AND USES THEREOF | ABBOTT LAB (US) | 2006-07-12 | — | — | EP | disclosed |
| EP-1513866-A2 | ASSAY CONJUGATE AND USES THEREOF | Abbott Laboratories (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-1373897-A1 | RECOVERY OF ENZYME ACTIVITY FROM ENVELOPED VIRUSES | Cavidi Tech AB (SE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003106649-A2 | ASSAY CONJUGATE AND USES THEREOF | ABBOTT LABORATORIES (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030232386-A1 | Assay conjugate and uses thereof | ABBOTT LABORATORIES | 2003-12-18 | — | — | US | disclosed |
| WO-2002082088-A1 | RECOVERY OF ENZYME ACTIVITY FROM ENVELOPED VIRUSES | CAVIDI TECH AB (SE) | 2002-10-17 | — | — | WO | disclosed |
| US-4510147-A | FREE RADICA INHIBITION; ATHEROSCLEROSIS; RADIOLOGY; ANTITUMOR AGENTS; SENSITIZERS | MATERIAL VEGYIPARI SZOVETKEZET (HU) | 1985-04-09 | — | — | US | disclosed |