⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194826 | 1.00 | — | — | |
| SCHEMBL13843772 | 0.74 | MAPK1 (0.42) | — | |
| SCHEMBL23748142 | 0.72 | — | — | |
| SCHEMBL18030765 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL26009355 | 0.72 | HTT (0.40) | — | |
| SCHEMBL9763750 | 0.72 | — | — | |
| SCHEMBL26009361 | 0.71 | HTT (0.47) | — | |
| SCHEMBL13334623 | 0.71 | — | — | |
| SCHEMBL6160227 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL15561538 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136133-A1 | PHENYLPIPERAZINAMIDE DERIVATIVES MODIFIED WITH ALIPHATIC AMINO ACID FRAGMENTS FOR THE TREATMENT OF NEUROLOGICAL DISEASES | Uniwersytet Jagielloński (PL) | 2025-06-26 | — | — | WO | disclosed |
| EP-1545572-A4 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | DENDREON CORP (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1545572-A2 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | Dendreon Corporation (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040067999-A1 | Carbazole derivatives and their use as neuropeptide y5 receptor ligands | ASTRAZENECA AB (SE) | 2004-04-08 | — | — | US | disclosed |
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002095007-A2 | CONJUGATES ACTIVATED BY CELL SURFACE PROTEASES AND THERAPEUTIC USES THEREOF | DENDREON SAN DIEGO LLC (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |