SCHEMBL5665461

SCHEMBL5665461

O=[N+]([O-])c1ccc(O)c(N=Nc2ccc(O)cc2O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.73
MEN1 O00255 4/20 0.73
MAPT P10636 4/20 0.73
KMT2A Q03164 4/20 0.73
POLB P06746 3/20 0.73
HTT P42858 2/20 0.73
LMNA P02545 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73
KDM4E B2RXH2 2/20 0.54
SMN1; SMN2 Q16637 3/20 0.49
TSHR P16473 2/20 0.49
GPR35 Q9HC97 2/20 0.49
HPGD P15428 2/20 0.49
EGFR P00533 1/20 0.49
TP53 P04637 1/20 0.49
MAPK1 P28482 1/20 0.49
GAA P10253 1/20 0.47
THRB P10828 1/20 0.47
ALOX15 P16050 1/20 0.46
PHGDH O43175 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11693093 1.00 ALDH1A1 (0.73) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL11694225 0.92 ALDH1A1 (0.79) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL11694220 0.92 ALDH1A1 (0.79) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL11306759 0.86 ALDH1A1 (0.71) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL11306764 0.86 ALDH1A1 (0.71) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL29366468 0.84 MAPT (1.00) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL1289510 0.84 MAPT (1.00) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL1289511 0.84 MAPT (1.00) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL10898315 0.84 MEN1 (0.57) ALDH1A1MEN1MAPTKMT2APOLB
SCHEMBL31307193 0.84 MEN1 (0.57) ALDH1A1MEN1MAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086115-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER Intergen Company (US) 2001-03-28 EP claimed
WO-1999064431-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER INTERGEN COMPANY (US) 1999-12-16 WO claimed
US-7116209-B2 Strain gauges COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2006-10-03 US disclosed
EP-1423269-A4 STRAIN GAUGES COMMW SCIENT IND RES ORG (AU) 2006-06-14 EP disclosed
US-20040250750-A1 Functionalised nanoparticle films COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-12-16 US disclosed
US-20040239475-A1 Strain gauges COMMONWELTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-12-02 US disclosed
EP-1423439-A1 FUNCTIONALISED NANOPARTICLE FILMS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-06-02 EP disclosed
EP-1423269-A1 STRAIN GAUGES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-06-02 EP disclosed
US-6531581-B1 When incorporated into hairpin oligonucleotides these quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide SEROLOGICALS, INC. 2003-03-11 US disclosed
WO-2003018307-A1 STRAIN GAUGES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-03-06 WO disclosed
WO-2003018645-A1 FUNCTIONALISED NANOPARTICLE FILMS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-03-06 WO disclosed
EP-1086115-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER Intergen Company (US) 2001-03-28 EP disclosed
WO-1999064431-A2 PURINES AND PYRIMIDINES LINKED TO A QUENCHER INTERGEN COMPANY (US) 1999-12-16 WO disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed