SCHEMBL56658

SCHEMBL56658

CSc1ccc2c(c1)C(=O)CCO2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.46
MAOA P21397 1/20 0.46
GRM5 P41594 6/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
LMNA P02545 1/20 0.40
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.37
HPGD P15428 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
DYRK1A Q13627 1/20 0.35
DYRK2 Q92630 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
TYMS P04818 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69391 0.87 MAOB (0.58) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL6591192 0.84 MAOB (0.44) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL6592049 0.83 MAOB (0.50) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL1985752 0.83 MAOB (0.46) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL10720650 0.83 MAOB (0.46) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL1985123 0.83 MAOB (0.46) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL2074306 0.83 MAOB (0.46) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL10443981 0.83 SMN1; SMN2 (0.41) MAOBMAOAALDH1A1SMN1; SMN2LMNA
SCHEMBL6087084 0.83 MAOB (0.43) MAOBMAOAGRM5ALDH1A1SMN1; SMN2
SCHEMBL10363956 0.80 MAOB (0.43) MAOBMAOAGRM5ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085439-B1 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORP (JP) 2013-10-02 EP disclosed
US-8128843-B2 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2085439-A1 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM Corporation (JP) 2009-08-05 EP disclosed
US-20090186163-A1 PHOTOCURABLE COMPOSITION, PHOTOCURABLE INK COMPOSITION, PROCESS FOR PRODUCING PHOTOCURED MATERIAL, AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-07-23 US disclosed
EP-0212428-B1 DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS SCHERING CORPORATION (US) 1990-06-06 EP disclosed
EP-0092386-B1 HYDANTOIN THERAPEUTIC AGENTS ALCON LABORATORIES, INC. (US) 1988-08-10 EP disclosed
US-4731364-A Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1988-03-15 US disclosed
EP-0212428-A1 Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals SCHERING CORPORATION (US) 1987-03-04 EP disclosed
US-4464385-A 6-METHYL-THIO OR-SULFINYL(SPIRO-CHROMAN-IMIDAZOLIDINEDIONES) ALCON LABORATORIES, INC. (US) 1984-08-07 US disclosed
WO-1983003542-A1 HYDANTOIN THERAPEUTIC AGENTS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092386-A2 Hydantoin therapeutic agents ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed