Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114795 | 0.87 | MAOB (0.58) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL1985123 | 0.83 | MAOB (0.46) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL10720650 | 0.83 | MAOB (0.46) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL56658 | 0.83 | MAOB (0.46) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL1985752 | 0.83 | MAOB (0.46) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL6592049 | 0.83 | MAOB (0.50) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL6591192 | 0.81 | MAOB (0.44) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL8138285 | 0.80 | MAOB (0.46) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL10363956 | 0.80 | MAOB (0.43) | MAOBMAOAGRM5NPC1ALDH1A1 | |
| SCHEMBL10363838 | 0.80 | MAOB (0.43) | MAOBMAOAGRM5NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284892-A | Stimulus-responsive hyaluronic acid film with adjustable afterglow color | 天津大学浙江绍兴研究院 | 2023-06-23 | — | — | CN | claimed |
| CN-110698456-B | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2021-05-14 | — | — | CN | claimed |
| CN-114031603-B | Thiochroman 4-ketone compound, preparation method thereof and UV (ultraviolet) photocuring combination system thereof | 深圳市大衍创新材料科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |
| CN-116284892-A | Stimulus-responsive hyaluronic acid film with adjustable afterglow color | 天津大学浙江绍兴研究院 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023026884-A1 | CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID STATE IMAGE SENSOR, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR | 富士フイルム株式会社 | 2023-03-02 | — | — | WO | disclosed |
| CN-114031603-A | Thiochromane 4-ketone compound, preparation method thereof and UV (ultraviolet) photocuring combination system thereof | 深圳市芯研材料科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-110698456-B | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2021-05-14 | — | — | CN | disclosed |
| CN-110698456-A | Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof | 重庆医药高等专科学校 | 2020-01-17 | — | — | CN | disclosed |
| US-8263764-B2 | IL-12 Modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2012-09-11 | — | — | US | disclosed |
| US-20110294798-A1 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2011-12-01 | — | — | US | disclosed |
| US-4352808-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SCHERING CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0054233-A1 | Novel benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans, processes for their preparation and antimicrobial compositions containing them | SCHERING CORPORATION (US) | 1982-06-23 | — | — | EP | disclosed |
| US-4282229-A | FOR DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4268516-A | [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4258054-A | ANTIDIABETIC | PFIZER INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4210756-A | Tetrahydroquinoline hydantoins for chronic diabetic complications | PFIZER INC. (US) | 1980-07-01 | — | — | US | disclosed |
| US-4209630-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4147795-A | ENZYME INHIBITORS | PFIZER INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4117230-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294798-A1 | IL-12 MODULATORY COMPOUNDS | IL2, IL4, IL15 | MAOB 2302/4885MAOA 2199/4885GRM5 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.