SCHEMBL5666137

SCHEMBL5666137

O/N=C\c1cccc(/C=N\O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
FURIN P09958 1/20 0.52
POLB P06746 2/20 0.47
CHRM5 P08912 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
PKM P14618 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPK1 P28482 1/20 0.44
THPO P40225 1/20 0.44
GRM5 P41594 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5666139 1.00 KDM4E (0.58) KDM4EALDH1A1L3MBTL1FURINPOLB
SCHEMBL8241465 0.89 ALDH1A1 (0.48) KDM4EALDH1A1L3MBTL1FURINPOLB
SCHEMBL10938534 0.89 ALDH1A1 (0.48) KDM4EALDH1A1L3MBTL1FURINPOLB
SCHEMBL4283272 0.85 GFER (0.56) KDM4EALDH1A1L3MBTL1CYP3A4CYP2D6
SCHEMBL3081450 0.85 GFER (0.56) KDM4EALDH1A1L3MBTL1CYP3A4CYP2D6
SCHEMBL3662156 0.85 GFER (0.56) KDM4EALDH1A1L3MBTL1CYP3A4CYP2D6
SCHEMBL5110843 0.84 ALDH1A1 (0.54) KDM4EALDH1A1L3MBTL1POLBRAB9A
SCHEMBL13269424 0.84 CYP19A1 (0.52) KDM4EALDH1A1L3MBTL1FURINPOLB
SCHEMBL2161608 0.84 NPC1 (0.69) KDM4EALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL2160781 0.84 ALDH1A1 (0.54) KDM4EALDH1A1L3MBTL1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240268-B1 DISCOLORATION-FAST DISPERSION ADHESIVES HAVING A PROLONGED POTLIFE CELANESE EMULSIONS GMBH (DE) 2006-12-13 EP disclosed
US-6730718-B1 POLYVINYL ESTER DISPERSIONS, WHOSE FILMS EXHIBIT INCREASED WATER RESISTANCE CELANESE EMULSIONS GMBH (DE) 2004-05-04 US disclosed
EP-1240268-A1 DISCOLORATION-FAST DISPERSION ADHESIVES HAVING A PROLONGED POTLIFE Clariant GmbH (DE) 2002-09-18 EP disclosed
WO-2001027214-A1 DISCOLORATION-FAST DISPERSION ADHESIVES HAVING A PROLONGED POTLIFE CLARIANT GMBH (DE) 2001-04-19 WO disclosed
EP-0686682-B1 Dispersion adhesives CLARIANT GMBH (DE) 1997-12-03 EP disclosed
EP-0686682-A1 Dispersion adhesives HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-13 EP disclosed