Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL5666458

NC(CSC[C@H](N)C(=O)O)C(=O)O.S

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.59
ARG2 P78540 1/20 0.59
NOS2 P35228 3/20 0.52
NOS1 P29475 2/20 0.52
NOS3 P29474 1/20 0.52
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48
GSR P00390 2/20 0.44
GRIK1 P39086 2/20 0.44
SLC1A1 P43005 2/20 0.44
GRIK2 Q13002 2/20 0.44
GRM1 Q13255 2/20 0.44
GRM2 Q14416 2/20 0.44
SLC7A5 Q01650 1/20 0.44
GRM8 O00222 1/20 0.44
GRM6 O15303 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CYP1A2 P05177 1/20 0.44
GRM5 P41594 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378137 0.97 ARG1 (0.61) ARG1ARG2NOS2NOS1NOS3
SCHEMBL36935 0.97 ARG1 (0.61) ARG1ARG2NOS2NOS1NOS3
SCHEMBL36933 0.97 ARG1 (0.61) ARG1ARG2NOS2NOS1NOS3
SCHEMBL29393779 0.97 ARG1 (0.61) ARG1ARG2NOS2NOS1NOS3
SCHEMBL36934 0.97 ARG1 (0.61) ARG1ARG2NOS2NOS1NOS3
Selenium SCHEMBL29993624 0.94 ARG1 (0.59) ARG1ARG2NOS2NOS1NOS3
SCHEMBL995282 0.90 ARG1 (0.55) ARG1ARG2NOS2NOS1NOS3
SCHEMBL995284 0.90 ARG1 (0.55) ARG1ARG2NOS2NOS1NOS3
Alanine SCHEMBL9937851 0.87 ARG1 (0.53) ARG1ARG2NOS2NOS1NOS3
Alanine SCHEMBL9937853 0.87 ARG1 (0.53) ARG1ARG2NOS2NOS1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108472277-A Compositions and methods for treating homocystinuria 科罗拉多州立大学董事会法人团体 2018-08-31 CN disclosed
EP-1549757-A4 METHOD OF PURIFYING LANTIBIOTICS IMMUCELL CORP (US) 2006-03-15 EP disclosed
EP-1549757-A1 METHOD OF PURIFYING LANTIBIOTICS Immucell Corporation (US) 2005-07-06 EP disclosed
US-6794181-B2 SUCH AS NISIN; COMPRISES INCUBATION MIXTURE CONTAINING A PROTEOLYTIC ENZYME; SOLID PHASE SYNTHESIS IMMUCELL CORPORATION 2004-09-21 US disclosed
WO-2004033704-A1 METHOD OF PURIFYING LANTIBIOTICS IMMUCELL CORPORATION (US) 2004-04-22 WO disclosed
US-20040072333-A1 Using proteolysis to degrade non-nisin polypeptide and impurities and enrich mixtures for nisin peptide antibiotics IMMUCELL CORPORATION (US) 2004-04-15 US disclosed