Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695944 | 0.90 | TSHR (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL146236 | 0.86 | THRB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29603148 | 0.86 | THRB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL27637386 | 0.80 | TSHR (0.54) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17430700 | 0.78 | THRB (0.51) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15361829 | 0.78 | TSHR (0.44) | POLBAPEX1HTTTDP1TSHR | |
| Benzene SCHEMBL641783 | 0.77 | THRB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| O-Xylene SCHEMBL23120128 | 0.77 | TSHR (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29315497 | 0.77 | POLB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL3409621 | 0.76 | MAOB (0.50) | TSHRTHRBMAOBTHRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307111-B2 | Polymer particles containing a cross-linked polymer core and a linear non-cross-linked polymer shell, and toner formed therefrom | XEROX CORPORATION (US) | 2007-12-11 | — | — | US | disclosed |
| US-20060135650-A1 | Polymer particles containing a cross-linked polymer core and a linear non-cross-linked polymer shell, and toner formed therefrom | XEROX CORPORATION (US) | 2006-06-22 | — | — | US | disclosed |