SCHEMBL5667149

SCHEMBL5667149

O=C(O)c1cc(C#Cc2ccccc2)ccc1-c1ccc(C#Cc2ccccc2)cc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.71
AKR1C2 P52895 1/20 0.56
AKR1C1 Q04828 1/20 0.56
FFAR1 O14842 6/20 0.52
GRM5 P41594 6/20 0.51
APP P05067 1/20 0.46
FOLH1 Q04609 1/20 0.45
PTPN11 Q06124 1/20 0.45
FFAR4 Q5NUL3 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542005 0.86 HNF4A (0.73) HNF4AAKR1C2AKR1C1FFAR1GRM5
SCHEMBL5669125 0.85 HNF4A (0.66) HNF4AAKR1C2AKR1C1FFAR1GRM5
SCHEMBL15809275 0.81 HNF4A (0.67) HNF4AAKR1C2AKR1C1FFAR1GRM5
SCHEMBL14252115 0.81 HNF4A (0.67) HNF4AAKR1C2AKR1C1FFAR1APP
SCHEMBL2620526 0.80 HNF4A (0.65) HNF4AAKR1C2AKR1C1FFAR1GRM5
SCHEMBL27178395 0.79 HNF4A (0.63) HNF4AAKR1C2AKR1C1FFAR1PTPN11
SCHEMBL15941312 0.79 HNF4A (0.74) HNF4AAKR1C2AKR1C1FFAR1APP
SCHEMBL23143181 0.79 HNF4A (0.63) HNF4AAKR1C2AKR1C1FFAR1ALDH1A1
SCHEMBL10054179 0.79 HNF4A (0.63) HNF4AAKR1C2AKR1C1FFAR1GRM5
SCHEMBL27178358 0.78 HNF4A (0.62) HNF4AAKR1C2AKR1C1FFAR1PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed