⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666736 | 0.87 | CYP2C9 (0.38) | — | |
| SCHEMBL19597063 | 0.75 | — | — | |
| SCHEMBL112080 | 0.75 | — | — | |
| SCHEMBL389017 | 0.72 | — | — | |
| SCHEMBL1169137 | 0.72 | ALDH1A1 (0.50) | — | |
| SCHEMBL4137033 | 0.72 | PHF8 (0.38) | — | |
| SCHEMBL3874714 | 0.71 | — | — | |
| SCHEMBL9736805 | 0.69 | — | — | |
| SCHEMBL213654 | 0.69 | — | — | |
| SCHEMBL9329 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118001414-A | Responsive aggregating nano-chelators for anti-angiogenic enhancement interventions | 华中科技大学同济医学院附属协和医院 | 2024-05-10 | — | — | CN | claimed |
| CN-108186649-B | Application of propionyl amino chloro benzo [ d ] aza-quinazoline in preparing medicament for treating leukemia | 浙江工业大学 | 2020-05-26 | — | — | CN | claimed |
| US-9673408-B2 | Luminescent diazabenzimidazole carbene metal complexes | UDC IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | claimed |
| CN-101128413-A | Substituted oxyarenes | BAYER CROPSCIENCE AG (DE) | 2008-02-20 | — | — | CN | claimed |
| US-7125998-B2 | Rhodium and iridium complexes | MERCK PATENT GMBH (DE) | 2006-10-24 | — | — | US | claimed |
| CN-1346351-A | 1,2-benzothiazepines for the treatment of hyperlipidemic diseases | SEARLE & CO (US) | 2002-04-24 | — | — | CN | claimed |
| CN-119386015-A | Composition for treating hypertension | 乔治全球健康研究院 | 2025-02-07 | — | — | CN | disclosed |
| CN-118001414-A | Responsive aggregating nano-chelators for anti-angiogenic enhancement interventions | 华中科技大学同济医学院附属协和医院 | 2024-05-10 | — | — | CN | disclosed |
| CN-116603066-A | Composition for treating hypertension | 乔治全球健康研究院 | 2023-08-18 | — | — | CN | disclosed |
| CN-116327958-A | Composition for treating hypertension | 乔治全球健康研究院 | 2023-06-27 | — | — | CN | disclosed |
| EP-3424912-B1 | 2-AMINOTHIAZOLE DERIVATIVES, PREPARATION AND USE THEREOF | UNIV HUAZHONG SCIENCE TECH (CN) | 2022-09-07 | — | — | EP | disclosed |
| CN-113473992-A | Compounds for the treatment and prevention of complications associated with neutrophil extracellular traps | 澳大利亚国立大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-112334137-A | Orphan nuclear receptor modulators for NASH and other metabolic disorders | 埃默里大学 | 2021-02-05 | — | — | CN | disclosed |
| EP-0011370-A1 | Process for preparing 2-chlorosulfinyl-azetidinones | ELI LILLY AND COMPANY (US) | 1980-05-28 | — | — | EP | disclosed |
| US-4165315-A | CHLORINATION WITH AN N-CHLORO HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4165316-A | Process for preparing sulfinyl chlorides from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4159272-A | Process for 2-chlorosulfinylazetidin-4-ones | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4081440-A | Sulfinyl halides and their preparation from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4075007-A | N-chloro-chloroacetamides as herbicides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4075203-A | Process for preparing a 3-exomethylenecepham sulfoxide from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |