Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667642 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1817741 | 0.74 | HTT (0.41) | ALDH1A1TDP1MAPTCYP1A2CYP3A4 | |
| SCHEMBL1819681 | 0.74 | HTT (0.39) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL16389747 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL15716419 | 0.73 | S1PR4 (0.48) | ALDH1A1TDP1MAPTHPGDCYP1A2 | |
| SCHEMBL1550181 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1550138 | 0.73 | POLB (0.47) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL6106344 | 0.72 | DAO (0.34) | ALDH1A1 | |
| SCHEMBL2298324 | 0.72 | CYP1A2 (0.45) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD | |
| SCHEMBL21331700 | 0.72 | MAPT (0.60) | ALDH1A1TDP1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682508-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005049573-A1 | PHENYL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-02 | — | — | WO | disclosed |