Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389981 | 0.88 | POLB (0.37) | TLR7TLR8NUDT1PDE10AALDH1A1 | |
| SCHEMBL9388638 | 0.86 | PDE10A (0.38) | TLR7PDE10ATSHRCYP1A2 | |
| SCHEMBL4317842 | 0.82 | TLR7 (0.53) | TLR7TLR8NUDT1MEN1TSHR | |
| SCHEMBL9036377 | 0.81 | NPC1 (0.40) | TLR7PDE10AALDH1A1MEN1KMT2A | |
| SCHEMBL4135751 | 0.81 | TLR7 (0.45) | TLR7TLR8NUDT1PDE10AALDH1A1 | |
| SCHEMBL1706194 | 0.80 | TLR7 (0.67) | TLR7TLR8NUDT1 | |
| SCHEMBL16802296 | 0.79 | PDE10A (0.49) | TLR7TLR8NUDT1PDE10AMEN1 | |
| SCHEMBL6105237 | 0.79 | TLR8 (0.48) | TLR7TLR8NUDT1PDE10AALDH1A1 | |
| SCHEMBL18179115 | 0.78 | TLR7 (0.49) | TLR7TLR8NUDT1PDE10AALDH1A1 | |
| SCHEMBL4756005 | 0.78 | TLR7 (0.46) | TLR7TLR8NUDT1PDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318812-A1 | METHODS FOR DELAYING RECURRENCE OF HERPES VIRUS SYMPTOMS | 3M Innovative Properties Company (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022125-A1 | METHODS FOR DELAYING RECURRENCE OF HERPES VIRUS SYMPTOMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2014201245-A1 | TLR-9 AGONIST WITH TLR-7 AND/OR TLR-8 AGONIST FOR TREATING TUMORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-12-18 | — | — | WO | disclosed |
| EP-1461074-A4 | AGENTS FOR ENHANCING THE IMMUNE RESPONSE | BECTON DICKINSON CO (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-1608282-A2 | METHODS FOR DIAGNOSING SKIN LESIONS | 3M Innovative Properties Company (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1461074-A2 | AGENTS FOR ENHANCING THE IMMUNE RESPONSE | Becton, Dickinson and Company (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2004080293-A2 | METHODS FOR DIAGNOSING SKIN LESIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-09-23 | — | — | WO | disclosed |
| WO-2003015694-A2 | AGENTS FOR ENHANCING THE IMMUNE RESPONSE | BECTON, DICKINSON AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |