SCHEMBL1706194

SCHEMBL1706194

CCOCc1nc2cnc3ccccc3c2n1CC(C)(C)O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.67
TLR8 Q9NR97 10/20 0.67
NUDT1 P36639 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22158729 0.92 TLR7 (0.58) TLR7TLR8NUDT1
SCHEMBL4317842 0.89 TLR7 (0.53) TLR7TLR8NUDT1
SCHEMBL5451703 0.89 TLR7 (0.56) TLR7TLR8NUDT1
SCHEMBL4130348 0.89 TLR7 (0.57) TLR7TLR8NUDT1
SCHEMBL1890829 0.88 TLR7 (0.52) TLR7TLR8NUDT1
SCHEMBL5617120 0.87 TLR7 (0.54) TLR7TLR8NUDT1
SCHEMBL22158693 0.87 TLR7 (0.52) TLR7TLR8NUDT1
SCHEMBL1895853 0.87 TLR7 (0.53) TLR7TLR8NUDT1
SCHEMBL4313723 0.87 TLR7 (0.55) TLR7TLR8NUDT1
SCHEMBL4245396 0.87 TLR7 (0.55) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210330664-A1 PHARMACEUTICAL COMPOSITIONS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2021-10-28 US claimed
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2021-06-03 US claimed
CN-110769827-A Pharmaceutical composition 博笛生物科技有限公司 2020-02-07 CN claimed
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2015-12-17 US claimed
EP-2950649-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY Wellstat Therapeutics Corporation (US) 2015-12-09 EP claimed
WO-2014120995-A2 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY WELLSTAT THERAPEUTICS CORPORATION (US) 2014-08-07 WO claimed
WO-2008052126-A2 OINTMENT COMPRISING PHOSPHATIDYLSERINE AS ACTIVE AGENT FOR CANCER TREATMENT UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2008-05-02 WO claimed
WO-2025103490-A1 N-OXIDE IMMUNE AGONISTS ACTIVATION BY RADIOTHERAPY Beijing Changping Laboratory (CN) 2025-05-22 WO disclosed
US-12295970-B2 Imidazoquinoline compounds and prodrugs thereof UNIVERSITY OF KANSAS (US) 2025-05-13 US disclosed
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY PHARMA CINQ, LLC 2025-01-30 US disclosed
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity PHARMA CINQ, LLC (US) 2024-11-12 US disclosed
US-12030940-B2 Immunotherapeutic tumor treatment method NEKTAR THERAPEUTICS (US) 2024-07-09 US disclosed
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US disclosed
US-5977366-A 1-substituted, 2-substituted 1H-imidazo[4,5-c] quinolin-4-amines 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-11-02 US disclosed
EP-0582581-B1 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES MINNESOTA MINING & MFG (US) 1999-05-06 EP disclosed
EP-0872478-A2 Intermediates for the preparation of 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-21 EP disclosed
US-5741909-A PHARMACEUTICAL COMPOSITIONS WHICH ACT AS ANTIVIRAL AGENTS, INDUCE BIOSYNTHESIS OF INTERFERON AND INHIBIT TUMOR FORMATION IN ANIMALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-21 US disclosed
US-5605899-A VIRICIDES, BIOSYNTHESIS OF INTERFERONS, ANTITUMOR AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-25 US disclosed
US-5389640-A Viricides, antitumor agents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-14 US disclosed
WO-1992015582-A1 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163476-A1 IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY NOD1, NLRP3, AADAC TLR7 456/4885TLR8 63/4885NUDT1 713/4885
US-20250034139-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS TLR7 380/4885TLR8 87/4885NUDT1 428/4885
US-20150361077-A1 AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY AADAC, CASP1, AAAS TLR7 380/4885TLR8 87/4885NUDT1 428/4885
US-12295970-B2 Imidazoquinoline compounds and prodrugs thereof TLR7, TLR8, TLR1 TLR7 1/4885TLR8 2/4885NUDT1 592/4885
US-12139483-B2 Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity NOD1, NLRP3, AADAC TLR7 456/4885TLR8 63/4885NUDT1 713/4885
US-12030940-B2 Immunotherapeutic tumor treatment method CD274, TLR7, PDCD1LG2 TLR7 2/4885TLR8 5/4885NUDT1 2779/4885
US-20210330664-A1 PHARMACEUTICAL COMPOSITIONS PLA2G2C, SFPQ, PRNP TLR7 4767/4885TLR8 4832/4885NUDT1 346/4885
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 TLR7 147/4885TLR8 313/4885NUDT1 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.