Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958234 | 0.95 | CHEK1 (0.44) | ALDH1A1CHEK1PTK2MELKKCNH2 | |
| SCHEMBL5669375 | 0.89 | ALDH1A1 (0.38) | ALDH1A1ACKR3RAB9AKCNH2MCHR1 | |
| SCHEMBL5667930 | 0.89 | ACKR3 (0.41) | ALDH1A1ACKR3RAB9AMELKKCNH2 | |
| SCHEMBL5669317 | 0.89 | ALDH1A1 (0.40) | ALDH1A1TP53KHKMEN1GAA | |
| SCHEMBL5669360 | 0.86 | BTK (0.39) | ALDH1A1ACKR3KCNH2BTKMCHR1 | |
| SCHEMBL5669394 | 0.86 | BTK (0.39) | ALDH1A1ACKR3KCNH2BTKMCHR1 | |
| SCHEMBL5668095 | 0.85 | ALDH1A1 (0.38) | ALDH1A1BTK | |
| SCHEMBL5667484 | 0.85 | ALDH1A1 (0.38) | ALDH1A1BTK | |
| SCHEMBL5667034 | 0.85 | ALDH1A1 (0.38) | ALDH1A1BTK | |
| SCHEMBL3836653 | 0.83 | ALDH1A1 (0.40) | ALDH1A1ACKR3KCNH2MCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2006-11-02 | — | — | US | claimed |
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247269-A1 | Thienopyridone derivatives as kinase inhibitors | MAPKAPK2, MAP3K6, MAP3K12 | ALDH1A1 2307/4885ACKR3 934/4885CHEK1 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.