SCHEMBL5669496

SCHEMBL5669496

CCCCC#Cc1cccc(C(=O)O)c1C(C)(C)c1c(C#CCCCC)cccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.46
KDM4E B2RXH2 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
APEX1 P27695 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CYSLTR2 Q9NS75 1/20 0.40
CYSLTR1 Q9Y271 1/20 0.40
TSHR P16473 3/20 0.39
MMP2 P08253 1/20 0.38
MMP12 P39900 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5666941 0.83 KDM4E (0.50) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL19331451 0.83 KDM4E (0.56) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL5006713 0.82 KDM4E (0.49) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL4790549 0.79 CYSLTR2 (0.53) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL3249278 0.78 APEX1 (0.46) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL5667800 0.78 KDM4E (0.38) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL2747391 0.78 CYP3A4 (0.46) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL5669455 0.78 KDM4E (0.44) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL5823360 0.78 CYSLTR2 (0.47) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19
SCHEMBL20503373 0.78 CYSLTR2 (0.47) CYP3A4KDM4ESMN1; SMN2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed