Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139643 | 0.88 | CYP2C19 (0.45) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5666941 | 0.83 | KDM4E (0.50) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL19331451 | 0.83 | KDM4E (0.56) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5006713 | 0.82 | KDM4E (0.49) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL4790549 | 0.79 | CYSLTR2 (0.53) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5669496 | 0.78 | CYP3A4 (0.46) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3266797 | 0.78 | HTT (0.47) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5669455 | 0.78 | KDM4E (0.44) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL5823360 | 0.78 | CYSLTR2 (0.47) | APEX1CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL20503373 | 0.78 | CYSLTR2 (0.47) | APEX1CYP3A4CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315709-B1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| EP-1315709-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016339-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |