Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670017 | 0.92 | IDH2 (0.34) | IDH2ADRB1TRPV3IDH1 | |
| SCHEMBL5669633 | 0.84 | IDH2 (0.33) | IDH2ADRB1TRPV3IDH1 | |
| SCHEMBL5670975 | 0.84 | IDH2 (0.33) | IDH2ADRB1TRPV3IDH1 | |
| SCHEMBL5668777 | 0.83 | IDH2 (0.37) | IDH2ADRB1IDH1 | |
| SCHEMBL5669580 | 0.82 | CETP (0.34) | IDH2IDH1 | |
| SCHEMBL5669788 | 0.75 | CETP (0.35) | — | |
| SCHEMBL6858377 | 0.72 | CETP (0.41) | — | |
| SCHEMBL5669307 | 0.70 | CETP (0.35) | — | |
| SCHEMBL1244525 | 0.69 | CETP (0.35) | IDH1 | |
| SCHEMBL6571577 | 0.68 | CETP (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | claimed |
| EP-1404302-A1 | PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AMORPHOUS DRUG | Pfizer Products Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1401503-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000235-A9 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PROD INC (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003000294-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000238-A1 | PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AMORPHOUS DRUG | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |