SCHEMBL5669652

SCHEMBL5669652

Cc1cc(N=C=O)ccc1CN=C=O

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.53
TRPA1 O75762 1/20 0.53
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 1/20 0.41
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483400 0.86 CYP3A4 (0.58) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL26469 0.85 CYP3A4 (0.56) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL10968102 0.84 CYP3A4 (0.47) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL10965734 0.84 CYP3A4 (0.47) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL3407573 0.82 CYP3A4 (0.58) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL10963787 0.80 CYP3A4 (0.44) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL10962825 0.80 CYP3A4 (0.44) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL10962578 0.80 CYP3A4 (0.44) CYP3A4TRPA1MAPK1TDP1TSHR
SCHEMBL28725527 0.79 PYCR1 (0.46) TDP1
SCHEMBL28580712 0.79 CYP3A4 (0.42) CYP3A4TRPA1MAPK1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1174531-B1 MOISTURE-ABSORBING/RELEASING SYNTHETIC FIBER AND FABRIC USING THE SAME ASAHI CHEMICAL IND (JP) 2006-12-13 EP disclosed
US-6403216-B1 HAVING HIGH ELONGATION, STRETCHING RECOVERY, STRENGTH AND COLORFASTNESS; POLYUREAURETHANE AND POLYETHERURETHANE COPOLYMERS; CLOTHINGS ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-06-11 US disclosed
EP-1174531-A1 MOISTURE-ABSORBING/RELEASING SYNTHETIC FIBER AND FABRIC USING THE SAME Asahi Kasei Kabushiki Kaisha (JP) 2002-01-23 EP disclosed
US-4512929-A POLYURETHANE MONOMERS, PLANT SAFENING AGENT BASF AKTIENGESELLSCHAFT (DE) 1985-04-23 US disclosed