Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729717 | 0.82 | LMNA (0.33) | TSHRALDH1A1 | |
| SCHEMBL12080810 | 0.79 | HDAC3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8071528 | 0.77 | TSHR (0.36) | CES2CES1TSHRALDH1A1 | |
| SCHEMBL7150118 | 0.76 | CES1 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3019506 | 0.76 | CES1 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15229727 | 0.75 | FFAR3 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9651120 | 0.75 | FFAR3 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28953060 | 0.75 | FFAR3 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8845045 | 0.73 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL8845043 | 0.73 | TSHR (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7025954-B2 | Materials for reshaping of essentially rigid keratinaceous surfaces | ESSTECH, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1148862-A4 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | ESSCHEM INC (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20030215635-A1 | Materials for reshaping of essentially rigid keratinaceous surfaces | ESSTECH, INC. | 2003-11-20 | — | — | US | disclosed |
| EP-1148862-A1 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | Esschem, Inc. (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000045775-A1 | MATERIALS AND METHODS FOR RESHAPING OF ESSENTIALLY KERATINACEOUS SURFACES | ESSCHEM, INC. (US) | 2000-08-10 | — | — | WO | disclosed |
| US-6080389-A | Materials and methods for reshaping of essentially rigid keratinaceous surfaces | ESSCHEM, INC. (US) | 2000-06-27 | — | — | US | disclosed |