Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 6/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | DDO | Q99489 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647758 | 0.67 | CYP1A2 (0.59) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL29353343 | 0.65 | ALDH1A1 (0.53) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL588459 | 0.65 | ALDH1A1 (0.53) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL8363928 | 0.65 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| Formaldehyde SCHEMBL28821851 | 0.64 | CYP1A2 (0.52) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL7130502 | 0.63 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL3295896 | 0.63 | ALDH1A1 (0.40) | CYP1A2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL5950773 | 0.62 | ALDH1A1 (0.56) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL5950767 | 0.61 | ALDH1A1 (0.50) | MEN1KMT2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL13302890 | 0.61 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465615-A4 | TRICYCLIC-BIS-ENONE DERIVATIVES AND METHODS OF USE THEREOF | DARTMOUTH COLLEGE (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1465615-A1 | TRICYCLIC-BIS-ENONE DERIVATIVES AND METHODS OF USE THEREOF | Trustees of Dartmouth College (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059339-A1 | TRICYCLIC-BIS-ENONE DERIVATIVES AND METHODS OF USE THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2003-07-24 | — | — | WO | disclosed |